Article Text

PDF

In-vitro antigonococcal activity of rosoxacin (WIN 35213).
  1. C A Warren,
  2. K P Shannon,
  3. I Phillips

    Abstract

    The in-vitro activity of rosoxacin against 173 isolates of Neisseria gonorrhoeae, including 17 beta-lactamase-producers, was tested by an agar dilution method. Of the isolates, 167 (including 16 of the beta-lactamase-producers) were inhibited by 0 . 06 mg/l of rosoxacin. The remaining six isolates, one of which produced beta-lactamase and the others were moderately resistant to penicillin, were inhibited by 0 . 12-0 25 mg/l of the compound. There was little correlation between the minimum inhibitory concentrations (MICs) of rosoxacin and penicillin, except for isolates with MICs of penicillin of 0 . 06-1 mg/l, for which correlation was good.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.