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Br J Vener Dis 1982;58:105-108 doi:10.1136/sti.58.2.105
  • Research Article

Effects of tampon components on growth and dissemination of Neisseria gonorrhoeae.

  1. R J Arko,
  2. K H Wong,
  3. K G Finley-Price,
  4. J K Rasheed

      Abstract

      Six components used in vaginal tampons were tested for their effects on a strain of Neisseria gonorrhoeae isolated from a patient with disseminated infection. Tampon components containing carboxymethyl cellulose or its derivative prolonged the in-vitro survival of gonococci and, when injected with mucin into mice, significantly (P less than 0.0001) increased the dissemination of gonococci from the peritoneal cavity. In contrast, a component extracted from rayon tampons reduced in-vitro survival and appeared to suppress gonococcal dissemination in mice. Since tampons are used by a large number of women at a time when the risk of developing complications from venereal infections are increased, their effects on potential urogenital pathogens warrant further study.

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