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Genitourin Med 1985;61:359-362 doi:10.1136/sti.61.6.359
  • Research Article

Oral amoxycillin, an alternative treatment for neurosyphilis.

  1. R E Morrison,
  2. S M Harrison,
  3. E C Tramont

      Abstract

      A serum amoxycillin concentration of 0.11 g/l was established as being treponemicidal in a rabbit model with orchitis. Seventeen patients treated with amoxycillin 2 g by mouth three times a day plus 500 mg probenecid twice a day attained treponemicidal CSF amoxycillin concentrations. Thus amoxycillin by mouth offers an effective alternative method for treating patients with neurosyphilis.

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