Article Text

PDF

Lymphocyte subpopulations in donovanosis assessed by monoclonal antibodies and immunoglobulins.
  1. V N Sehgal,
  2. M K Jain,
  3. V K Sharma
  1. Department of Dermatology and Venereology, Maulana Azad Medical College, New Delhi, India.

    Abstract

    The haematological profile and peripheral blood lymphocyte subpopulations of 36 patients with donovanosis were estimated by an indirect immunofluorescence technique using monoclonal antibodies. Concentrations of serum immunoglobulins (IgM, IgG, and IgA) were also estimated. The total leucocyte and lymphocyte counts were generally raised, as were total T lymphocyte, T4, and T8 counts. Patients with the hypertrophic variant, however, had decreased numbers of T lymphocytes and T8 cells and increased B cells and IgG. B lymphocyte counts and IgM and IgG concentrations were raised generally.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.