Sex Transm Infect 76:143 doi:10.1136/sti.76.2.143

Successful treatment of recalcitrant condyloma with topical cidofovir

  1. U R Hengge,
  2. G Tietze
  1. Department of Dermatology and Venerology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
  2. Hospital Pharmacy, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
  1. U R Henggedermatology{at}
  • Accepted 11 January 2000

Editor,—Despite the high prevalence of condylomata acuminata, their treatment remains unsatisfactory for both patients and physicians. Epidemiological studies estimated the prevalence of genital warts between 1–31% with a peak occurring in young adults.1 As a consequence, the economic burden of human papillomavirus (HPV) infection in the United States is estimated to exceed $8.5 billion per year.2 Current treatments rely on the ablation of warts (cryotherapy, laser vaporisation, electrodissection, or trichloroacetic acid) or the interruption of cell division (podophylox, intralesional or systemic interferon, and 5-fluorouracil). Recently, imiquimod has been successfully used as a topical immune response modifier for the treatment of external anogenital warts.3 However, there remains a substantial number of patients who fail to respond …