Sex Transm Infect 77:226 doi:10.1136/sti.77.3.226

Lichen sclerosus of the glans is significantly associated with penile carcinoma

  1. Giuseppe Micali1,
  2. Maria Rita Nasca1,
  3. Daniele Innocenzi2
  1. 1Dermatology Clinic, University of Catania, Italy
  2. 2Dermatology Clinic, University “La Sapienza,” Rome, Italy
  1. Giuseppe Micali, MD, Clinica Dermatologica, Università di Catania, Piazza S Agata La Vetere, 6, 95124 - Catania, Italy cldermct{at}
  • Accepted 22 March 2001

Editor,—We read with interest the article by Riddel et al on 66 men with penile lichen sclerosus (PLS) attending a department of genitourinary medicine.1 In this study, the authors found no cases of malignancy.

We have previously reported a retrospective study on the incidence of cancer on 86 cases of PLS retrieved from our histopathological files over a 10 year period (1987–97).2 In that study, five cases showed malignant transformation—namely, squamous cell carcinoma (SCC) (three cases), in situ carcinoma (one case), and verrucous carcinoma (one case).

Since that report, we decided to interview all PLS patients in order to rule out any further malignancy …