Susceptibilities of Neisseria gonorrhoeae to fluoroquinolones and other antimicrobial agents in Hyogo and Osaka, Japan

Table 2

MIC₅₀ values of structurally unrelated antimicrobial agents for fluoroquinolone sensitive and fluoroquinolone less sensitive N gonorrhoeae

Antimicrobial agents	Ciprofloxacin			Levofloxacin			Gatifloxacin
Antimicrobial agents	Sensitive	Less sensitive*	p Value	Sensitive	Less sensitive*	p Value	Sensitive	Less sensitive*	p Value
*Less sensitive includes the category of intermediate and resistant according to the NCCLS guidelines, 2002.
Penicillin G	0.031	0.5	<0.001	0.375	0.5	0.0078	0.125	0.5	0.0079
Tetracycline	0.25	1	0.508	1	1	0.2152	4	1	0.7423
Cefixime	0.008	0.125	<0.001	0.078	0.125	0.1599	0.016	0.125	0.0541
Ceftriaxone	0.004	0.016	0.0006	0.01	0.016	0.0477	0.004	0.016	0.0384
Spectinomycin	32	32	0.2022	32	32	0.4734	32	32	0.8326