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Intestinal B cells in AIDS

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    There have been few studies of intestinal mucosal immunity in patients with HIV infection. Some have reported low numbers of IgA producing immunocytes in the gut mucosa but others have found normal numbers. Now researchers in Norway have demonstrated hyperactivation of intestinal B cells in patients with AIDS.

    They studied 31 patients (25 men) aged 26–52 years with HIV-1 infection (25 with …

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