Symptomatic urethritis is more prevalent in men infected with Mycoplasma genitalium than with Chlamydia trachomatis
- 1Department of Dermatology and Venereology, Örebro University Hospital, Sweden
- 2Department of Clinical Microbiology and Immunology, Örebro University Hospital, Sweden
- 3Mycoplasma Laboratory, Statens Serum Institut, Copenhagen, Denmark
- Correspondence to: Dr Lars Falk Department of Dermatology and Venereology, Örebro University Hospital, SE-701 85 Örebro, Sweden;
- Accepted 19 October 2003
Objectives: To study the prevalence, symptoms, and signs of Mycoplasma genitalium and Chlamydia trachomatis infections in men attending a Swedish STD clinic and to study the criteria for urethritis.
Methods: A cross sectional study among STD clinic attendees in Örebro, Sweden. Attendees were examined for microscopic urethritis and first void urine (FVU) was tested for M genitalium and C trachomatis.
Results: The prevalence of M genitalium and C trachomatis was 7% (34/512) and 12% (61/512), respectively. Dual infection was diagnosed in four men. In both infections 90% of the patients had signs of microscopic urethritis. M genitalium positive men had symptomatic urethritis significantly more often than those infected with C trachomatis (73% v 40%, RR 1.8; 95% CI 1.2 to 2.7). 63% of female partners of men infected with M genitalium were infected with M genitalium compared with chlamydial infection in 67% of female partners of men infected with C trachomatis. Non-chlamydial non-gonococcal urethritis without evidence of M genitalium infection was diagnosed in 180 men (35%). Symptoms and/or visible discharge were reported in 49% in this group.
Conclusions:M genitalium is a common infection associated with symptomatic urethritis and with a high prevalence of infected sexual partners supporting its role as a sexually transmitted infection.
Funded by the Research Committee of Örebro County Council, Örebro Medical Centre Research Foundation. The research ethic committee of Örebro County Council approved the study 1 November 1999.
Conflict of interest: None declared.