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Sex Transm Infect 2005;81:351-357 doi:10.1136/sti.2004.014027
  • Clinicopathological conference

Progressive neuropsychiatric problems following institution of highly active antiretroviral therapy

  1. R F Miller1,
  2. S S Dave1,
  3. J W Tang2,
  4. P J Shaw3,
  5. H R Jäger3,
  6. E G L Wilkins4
  1. 1Patrick Manson Unit, University College London Hospitals, and Mortimer Market Centre, Camden PCT, London WC1E 6AU, UK
  2. 2Department of Virology, University College London Hospitals, London W1T 4JF, UK
  3. 3Department of Imaging, University College London Hospitals, London WC1E 6DB, UK
  4. 4Department of Infectious Diseases, North Manchester General Hospital, Manchester M8 5RB, UK
  1. Correspondence to:
 Dr R F Miller
 Mortimer Market Centre, RFUCMS, University College London, London WC1E 6AU, UK; rmillergum.ucl.ac.uk
  • Accepted 29 November 2004

Abstract

A 31 year old HIV infected woman developed neuropsychiatric problems soon after starting highly active antiretroviral therapy (HAART). Despite modifying and subsequently stopping HAART her condition progressively worsened. Cranial magnetic resonance imaging revealed multiple areas of abnormal signal suggestive of either a vasculitis or demyelination.

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