Screening for Chlamydia trachomatis in asymptomatic women attending outpatient clinics in a large maternity hospital in Dublin, Ireland
- H M McMillan1,
- H O’Carroll2,
- J S Lambert3,
- K B Grundy3,
- M O’Reilly2,
- B Lennon3,
- C Collins4,
- T A Walsh1,
- M P Geary1,
- M T Cafferkey3,5
- 1Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin, Ireland
- 2Department of Midwifery, Rotunda Hospital, Dublin, Ireland
- 3Department of Microbiology, Rotunda Hospital, Dublin, Ireland
- 4Department of Statistics, Rotunda Hospital, Dublin, Ireland
- 5Department of Clinical Microbiology, Royal College of Surgeons, Ireland.
- Correspondence to: Dr J S Lambert Mater Misericordiae University Hospital, University College Dublin, 40 Eccles Street, Room S-15, Dublin 7, Ireland; jlambert{at}mater.ie
- Accepted 27 June 2006
- Published Online First 19 July 2006
Abstract
Background:Chlamydia trachomatis can cause a sexually transmitted infection, which, untreated, may result in considerable morbidity.
Methods: A prevalence study was conducted for C trachomatis using nucleic acid amplification technology in asymptomatic women, and certain risk factors that may be used to direct future screening strategies were assessed.
Results: The study population comprised 945 asymptomatic women, of whom 783 were attending antenatal clinics, 91 were attending infertility clinics and 71 were attending family planning clinics. An overall C trachomatis prevalence of 3.7% (35/945) was found, with the highest prevalence of 11.2% (22/196) in Irish single women aged <25 years. Logistic regression analysis showed that single status and age <25 years were independent, statistically significant predictors of C trachomatis infection.
Conclusion: These results support routine screening of asymptomatic women who are sexually active and aged <25 years. An opportunist active screening of all sexually active women independent of age should be additionally considered if resources permit.
Footnotes
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Funding: This study was funded by the Women’s’ Health Unit of the Eastern Regional Health Authority, Dublin, Ireland.
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Competing interests: None.
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Ethical approval: The Rotunda Hospital Research Ethics Committee approved this trial.







