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In a recent paper we concluded that an elevated IgA antibody response and the age of the infected individual (a total sum score of 7 times IgA titre plus individual’s age ⩾50.0 years) appeared to be of diagnostic value for (early) detection of lymphogranuloma venereum (LGV) proctitis (Sex Transm Infect 2007;83:330–4). Statistical analyses showed that the use of this total sum score had high diagnostic accuracy. As published previously, over 85% of the Rotterdam population of patients with L2 proctitis reported symptoms (rectal discharge and bleeding) and more than 70% had clinical manifestations (discharge and perianal erythema).1
We agree with de Vries et al and acknowledge the need for “simple and affordable diagnostic procedures to screen the (asymptomatic) population at …
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