Objectives To test the use of a rapid assessment tool to determine social network size, and to test whether social networks with a high density of HIV/sexually transmitted infection (STI) or substance using persons were independent predictors of HIV and STI status among men who have sex with men (MSM) using a rapid tool for collecting network information.

Methods We interviewed 609 MSM from 14 bars in San Diego, California, USA, using an enhanced version of the Priorities for Local AIDS Control Efforts (PLACE) methodology. Social network size was assessed using a series of 19 questions of the form ‘How many people do you know that have the name X?’, where X included specific male and female names (eg, Keith), use illicit substances, and have HIV. Generalised linear models were used to estimate average and group-specific network sizes, and their association with HIV status, STI history and methamphetamine use.

Results Despite possible errors in ascertaining network size, average reported network sizes were larger for larger groups. Those who reported having HIV infection or having past STI reported significantly more HIV infected and methamphetamine or popper using individuals in their social network. There was a dose-dependent effect of social network size of HIV infected individuals on self-reported HIV status, past STI and use of methamphetamine in the last 12 months, after controlling for age, ethnicity and numbers of sexual partners in the last year.

Conclusions Relatively simple measures of social networks are associated with HIV/STI risk, and may provide a useful tool for targeting HIV/STI surveillance and prevention.