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Emergent properties of HIV risk among injection drug users in Tallinn, Estonia: synthesis of individual and neighbourhood-level factors
  1. A Uusküla1,
  2. J M McMahon2,
  3. M Raag1,
  4. S Silm3,
  5. K Rüütel4,
  6. A Talu5,
  7. K Abel-Ollo5,
  8. R Ahas3,
  9. D C Des Jarlais6
  1. 1Department of Public Health, University of Tartu, Tartu, Estonia
  2. 2University of Rochester Medical Center, School of Nursing, Rochester, New York, USA
  3. 3Institute of Ecology and Earth Sciences, University of Tartu, Tartu, Estonia
  4. 4Department of Infectious Diseases and Drug Prevention, National Institute for Health Development, Tallinn, Estonia
  5. 5Estonian Drug Monitoring Centre, National Institute for Health Development, Tallinn, Estonia
  6. 6Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York, New York, USA
  1. Correspondence to Dr Anneli Uusküla, Department of Public Health, University of Tartu, Ravila 19, Tartu 50411, Estonia; anneli.uuskula{at}ut.ee

Abstract

Objectives HIV/AIDS risk is embodied within multiple levels including structural and social levels. The aim of this study was to assess the effects of neighbourhood characteristics on HIV prevalence among injection drug users (IDU) residing in the area of Tallinn, Estonia in 2007.

Methods A cross-sectional, multilevel design collecting individual-level data—a behaviour survey including data on self-reported residency and HIV antibody testing among 350 IDU and neighbourhood-level data—aggregate measures on socio-demo-economic residential characteristics from the 2000 Estonian census. Geocoding and multilevel modelling analysis was employed.

Results Among the 350 IDU recruited, earlier age at first injection, fentanyl as the main injection drug, receptive syringe sharing, main income source other than legal employment and ever attended a syringe exchange programme remained significantly associated with increased odds of anti-HIV positivity in the multivariable analysis involving individual effects with no predictors at the neighbourhood level. In the multilevel model, individual (earlier at IDU initiation AOR 1.86, 95% CI 1.01 to 3.44; injecting opioids AOR 4.43, 95% CI 2.74 to 7.18; receptive syringe sharing AOR 2.51, 95% CI 1.86 to 3.37; main income source other than work AOR 2.04, 95% CI 1.32 to 3.14; ever attended a syringe exchange programme AOR 2.58, 95% CI 1.83 to 3.61) and neighbourhood level (higher unemployment rate AOR 5.95, 95% CI 2.47 to 14.31; greater residential change AOR 1.89, 95% CI 1.09 to 3.26) emerged as significant predictors of individual HIV-positive status.

Conclusions Our results indicate that both individual-level and emergent neighbourhood-level factors contribute to HIV risk among IDU and are amenable for preventive interventions.

  • Epidemiology
  • Estonia
  • HIV
  • injecting drug use
  • injection drug user
  • multilevel analysis
  • neighbourhood

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Footnotes

  • Funding This study was supported by Civilian Research Development Foundation grant (ESX0-2722-TA-06), EU commission funded project ‘Expanding Network for Coordinated and Comprehensive Actions on HIV/AIDS Prevention among IDUs and Bridging Populations’ no 2005305, grant no SF0182128s02 from the Estonian Ministry of Education and Research, and grant R01 035174 ‘Risk Factors for AIDS in Drug Users’ from the US National Institute on Drug Abuse.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the the Ethics Review Board at the University of Tartu.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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