Article Text
Miscellanea
Letter
Fourth generation point of care testing for HIV: validation in an HIV-positive population
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- HIV
- HSV
- HIV testing
- HIV clinical care
- gay men
- LGV
- anorectal
- diagnosis
- risk factors
- primary HIV infection
- genitourinary medicine
- sexual behaviour
- mathematical model
- law ethics
- notification
- chlamydia
- epidemiology
Identification of primary HIV infection is valuable to reduce onward transmission and consider early antiretroviral therapy (ART). Fourth generation (4G) HIV tests detect p24 antigen in addition to antibody and therefore allow detection of HIV before antibody development. 4G point of care tests (POCTs) have been widely adopted despite an absence of prospective evidence and reports of reduced antigen sensitivity in primary HIV infection.1 The performance of the p24 component has not been evaluated in chronic infection and it is not known whether …
Footnotes
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.