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Epidemiology poster session 3: Burden of disease: PID
P1-S3.07 Relation between female infertility and sexually transmitted genital infections
  1. C Almanza,
  2. M Ricardo,
  3. A González
  1. Cira Garcia Clinic, Havana, Cuba

Abstract

Background Sexually transmitted genital infections can bring about severe consequences, among them the leading cause of pelvic inflammatory desease (PID), which can lead to infertility. The objective of this study was to determine the relation between female infertility and sexually transmitted genital infections.

Methods An analytic study of cases and controls was carried out in Ramón González Coro Gyneco-obstetric Hospital, Cuba, 2009. The studied cases were 89 infertile women with tube obstruction who were assessed in infertility consultations, and the controls were carried out in 100 pregnant women who were about to give birth. Vaginal and endocervical secretion samples were taken. Genital micoplasma was present; it was determined through bacteriological culture techniques. Trichomonas vaginalis, Candida spp, Bacterial vaginosis, Neisseria gonorrhoeae, Chlamydia trachomatis, as well as the presence of other genital pathologicals; were investigated. The test of exact probabilities of Fisher was carried out. A t student test was also done to determine significant defferencies among age averages. The RR was estimated by means of OR in tables 2×2, and its statistic meaning was determined through a CI at 95%, the aproximation of Woolf was used.

Results The age average in infertile women was of 30.4 years and in fertile woman 24.3 years. (4.486 -07), which is a highly significant difference. Bacterial vaginosis was detected in 72% of the infertile women and 30.9 % of pregnant women. Candida spp in 20% of infertile women and 65.4% of the controlled group. The presence of a highly significant statistic difference was proved when Fisher Test was applied. This difference was related to the distribution of microrganisms in both groups (p<0.0001). Mycoplasma hominis was isolated in 17% of infertile women and in 10% of fertile women. In the group of infertile women, Ureaplasma urealyticum was obtained in 42.70% of positive cultures; while in pregnant women, 2% was obtained. U urealyticum was not isolated in 57.30% of the infertile woman and in 98% of the pregnant ones. OR 83.92. CL for OR at 95% (17.37 to 397.05) statistically significant. In 54.30% of the infertile women and 98% of the pregnant ones, Chlamydia trachomatis was not isolated.

Conclusions The presence of bacterial vaginosis, U urealyticum, C trachomatis resulted to be a risk factor of female infertility.

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