Objectives The data concerning treatment of such sexually transmitted infection as Chlamydia trachomatis (CTR) among Ukrainian population are still limited and controversial. This information is of great scientific and health care interest. The aim of investigation is to find out efficiency of urogenital chlamydiosis treatment involving new effective ways of treatment and choose the most appropriate and expedient method of treatment, which would completely meet recommendations of WHO.
Methods We have analysed literature, records and recommendations concerning treatment of patients with chlamydial infection and concluded that there is no a perfect method of treatment, which would ensure complete clinical and laboratory cure. According to literature data, macrolids are good drugs with insignificant resistance to agent, nevertheless, recovery of a patient is, sometimes, incomplete due to complications. We have examined patients with urogenital chlamydiosis. All patients (n=134) were divided into four groups and treated with antimicrobial drugs jozamicyn and azytromicyn, and immunomodulators - manax and kagotsel. Patients from the 1st group (n=35) were treated with jozamicyn and manax, 2nd group (n=35) with azytromicyn and manax, 3rd group (n=34) with jozamicyn and kagotsel, 4th group (n=30) with azytromicyn and kagotsel.
Results Following treatment results of our investigation showed complete laboratory and clinical recovery in 93.2 % of patients from the 1st group, 98.1% of patients from the 2nd group, 91.8% of patients from the 3rd group, and 93.5% of patients from the 4th group.
Conclusion According to obtained data, our method of treatment, which was used for treatment of patients from the 2nd group, is the most appropriate for common application in the treatment of urogenital chlamydiosis
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