Sex Transm Infect 89:207-211 doi:10.1136/sextrans-2012-050648
  • Health services research
  • Original article

Who would use PrEP? Factors associated with intention to use among MSM in London: a community survey

  1. Anthony Nardone1
  1. 1HIV and STI Department, Health Protection Agency—Colindale, London, UK
  2. 2Centre for Sexual Health & HIV Research, Department of Infection & Population Health, Mortimer Market Centre, University College London, London, UK
  1. Correspondence to Adamma Aghaizu, HIV and STI Department, Health Protection Agency—Colindale, London NW9 5EQ, UK; adamma.aghaizu{at}
  • Accepted 19 August 2012
  • Published Online First 26 September 2012


Objective To assess current and intended future use of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) and characterise those attending sexual health clinics, the anticipated PrEP delivery setting.

Design Cross-sectional study.

Methods Self-administered survey of 842 HIV negative MSM recruited from social venues in London in 2011.

Results One in 10 (10.2%, 83/814, 95% CI 8.2% to 12.5%) and one in 50 (2.1%, 17/809, 95% CI 1.2% to 3.3%) reported having ever used post-exposure prophylaxis (PEP) and PrEP respectively. Half reported they would be likely to use PrEP if it became available as a daily pill (50.3%, 386/786, 95% CI 46.7% to 53.9%). MSM were more likely to consider future PrEP use if they were <35 years (adjusted OR (AOR) 1.57, 95% CI 1.16 to 2.14), had unprotected anal intercourse with casual partners (AOR 1.70, 95% CI 1.13 to 2.56), and had previously used PEP (AOR 1.94, 95% CI 1.17 to 3.24). Over half of MSM (54.8% 457/834 95% CI 51.3 to 58.2) attended a sexual health clinic the previous year. Independent factors associated with attendance were age <35 (AOR 2.29, 95% CI 1.68 to 3.13), and ≥10 anal sex partners in the last year (AOR 2.49, 95% CI 1.77 to 3.52).

Conclusions The concept of PrEP for HIV prevention in the form of a daily pill is acceptable to half of sexually active MSM in London. MSM reporting higher risk behaviours attend sexual health clinics suggesting this is a suitable setting for PrEP delivery.