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P2.129 Prevalence of Malaria in HIV Patients Under Cotrimoxazole, Case of Kindu, Maniema, D.R.Congo
  1. A M Bulabula1,
  2. N A Bulabula2,
  3. M Mbo3,
  4. T C Kayembe3
  1. 1Universite De Kindu, Kindu, Congo
  2. 2Provincial General Hospital of Bukavu, Bukavu, Congo
  3. 3Universite de Kisangani, Kisangani, Congo

Abstract

Background Malaria and HIV/AIDS are common in sub-Saharan Africa, their association aggravates the evolution of one another condition. HIV patients under cotrimoxazole have been reported to present less malaria cases. This study aims to determine the prevalence of malaria among HIV patients under Cotrimoxazole in Kindu.

Methods A sample of 1533 subjects, including 511 people living with HIV (PLHIV) attending the Voluntary Testing Centre (VCT) of the General Hospital of Kindu and 1022 controls was compiled. Thick and thin blood smears stained with Giemsa were used to search for asexual forms and determination of parasite species. The CD4 + lymphocytes count, in each patient was performed on FACS Count. We did a distribution of HIV patients in three groups according to the CD4+ range: 350 CD4+/mm3. Demographic data were recorded. The statistical analysis was performed on the software Epi Info 3.5.

Results 511 PLHIV 33.3% (95% CI, 31 –35.8) and 1022 controls 66.7% (95% CI, 62.2 to 69) are included in the sample. Females were dominant with 60.7% (95% CI, 58.2 to 63.2). The average age was 34.6 ± 12.6 years. The overall prevalence of parasitaemia 17.5% (268/1533, 95% CI: 15.6 to 19.6). Parasitaemia in PLHIV 13.7% (70/511) against 19.4% (198/1022) in controls (P < 0.05). Parasitaemia in PLHIV related to CD4 + was 16.4% (11/67) in the 350 CD4 +/mm3 (P < 0.05).

Conclusions Cotrimoxazole appears to protect PLHIV against malaria but there was not much difference with the controls.

  • Cotrimoxazole
  • HIV
  • Malaria

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