Article Text

PDF

O16.4 Human Papillomavirus in Very Young Men Who Have Sex with Men and the Potential Benefit from Vaccination
  1. H Zou1,
  2. A Morrow2,
  3. S Tabrizi3,
  4. A Grulich4,
  5. S Garland3,
  6. J Hocking5,
  7. C Bradshaw1,2,6,
  8. G Prestage4,7,
  9. C Fairley1,2,
  10. M Chen1,2
  1. 1School of Population Health, University of Melbourne, Carlton, Australia
  2. 2Melbourne Sexual Health Centre, Alfred Health, Carlton, Australia
  3. 3Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Australia
  4. 4Kirby Institute, University of New South UK, Sydney, Australia
  5. 5Centre for Women’s Health, Gender and Society, University of Melbourne, Carlton, Australia
  6. 6Department of Social and Preventive Medicine, Monash University, Clayton, Australia
  7. 7Australian Research Centre in Sex, Health and Society, Melbourne, Australia

Abstract

Background Homosexually active men are at increased risk for human papillomavirus (HPV) infection and HPV associated anal cancer. Prophylactic HPV vaccines have maximum efficacy in people who have not already been infected with HPV. This study aims to determine the prevalence of HPV among teenage MSM.

Methods Same sex attracted males aged 16 to 20 were recruited in Melbourne via clinics, universities, community events, media, social networking and peer recruitment. At baseline, 3, 6, and 12 months anal and penile swabs and an oral rinse were obtained to test for 37 HPV genotypes.

Results 200 men were recruited. At baseline 39% had at least one type of HPV DNA detected from at least one site. High risk (HR), low risk (LR) and quadrivalent vaccine (QV) preventable types were detected in 31% (95% CI: 25–37%), 30% (95% CI: 24–37%) and 23% (95% CI: 17–29%) of men respectively. Multiple types of any, HR, LR and QV preventable HPV were detected in 27%, 13%, 11% and 8% of men respectively. The site specific prevalence of any HPV detected from the oral cavity, penis and anus were 2%, 9% and 31% respectively: the prevalence of QV preventable types at these 3 sites was 0.5%, 4% and 20% respectively. Anal HPV was absent in 27 of 30 men who reported never receiving anal sex. Additional results of serology for HPV 6/11/16 and 18 will also be presented.

Conclusion In this study, the first to focus on early HPV acquisition among teenage MSM, HPV was common but in the minority. HPV vaccination prior to the onset of sexual activity is ideal; however, short of universal vaccination of school aged males, selected vaccination of teenage same sex attracted young men could still prevent many infections.

  • Human papillomavirus
  • men who have sex with men
  • vaccination

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.