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Lymphogranuloma venereum (LGV) re-emerged in Western Europe in 2003, and has arguably now regained endemic status in many countries. It remains largely contained within in a population of men who have sex with men (MSM) with high rates of other sexually transmitted infections (STIs) including HIV, though a first female case was reported in Sexually Transmitted Infections in 2012.1 The first outbreak of a re-emerging STI, LGV has been the subject of a good deal of interest from epidemiologists—for example a recent article reflected on the challenges of interpreting epidemic dynamics from cross-sectional data.2 This month, we bring together four papers on LGV in a mini-series. De Vries et al present a fascinating case series, with some important clinical lessons which will no doubt generate debate as …