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Chlamydia trachomatis L serovars and dominance of novel L2b ompA variants, USA
  1. Brian A Kendall1,2,
  2. Keith D Tardif3,
  3. Robert Schlaberg2,3
  1. 1 Department of Medicine, University of Utah, Salt Lake City, Utah, USA
  2. 2 Department of Pathology, University of Utah, Salt Lake City, Utah, USA
  3. 3 ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
  1. Correspondence to Dr Robert Schlaberg, Department of Pathology, University of Utah, 500 Chipeta Way, Salt Lake City, UT 84108, USA; robert.schlaberg{at}path.utah.edu

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Chlamydia trachomatis serovars L1, L2, L3 cause lymphogranuloma venereum (LGV). An epidemic of proctitis due to L serovar infections (mostly L2b) has emerged primarily among men who have sex with men (MSM) in Europe.1 In the USA, limited availability of diagnostic testing for LGV hinders diagnosis and reporting to public health agencies. We hypothesised that LGV may be underdiagnosed in the USA.

We collected 1027 C trachomatis-positive specimens referred to our national, academic reference laboratory for routine C trachomatis testing by APTIMA Combo 2 (AC2, Hologic, Bedford, Massachusetts, USA) or culture. We used a modified Centers for Disease Control …

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