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Chlamydia trachomatis serovars L1, L2, L3 cause lymphogranuloma venereum (LGV). An epidemic of proctitis due to L serovar infections (mostly L2b) has emerged primarily among men who have sex with men (MSM) in Europe.1 In the USA, limited availability of diagnostic testing for LGV hinders diagnosis and reporting to public health agencies. We hypothesised that LGV may be underdiagnosed in the USA.
We collected 1027 C trachomatis-positive specimens referred to our national, academic reference laboratory for routine C trachomatis testing by APTIMA Combo 2 (AC2, Hologic, Bedford, Massachusetts, USA) or culture. We used a modified Centers for Disease Control …
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