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U1 Asymptomatic lymphogranuloma venereum in known hiv positive msm: is it more common than we think?
  1. Daniel Ward1,
  2. Meg Boothby2,
  3. Penny Goold2,
  4. Emma Hathorn2
  1. 1University of Birmingham, Birmingham, UK
  2. 2Whittall Street Clinic, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

Abstract

Background/introduction The primary manifestation of lymphogranuloma venereum (LGV) infection in men who have sex with men (MSM) in the United Kingdom (UK) is haemorrhagic proctitis with very low levels of asymptomatic infection reported.

Aim(s)/objectives To evaluate LGV infection in MSM attending a large inner city sexual health and human immunodeficiency virus (HIV) clinic.

Methods Data was retrospectively collected on all MSM diagnosed with rectal Chlamydia trachomatis (CT) from 1st October 2010 to 30th June 2014. Information was collected on presentation, LGV diagnosis, HIV status, concurrent sexual infection, treatment and sexual contacts.

Results 583 MSM had a new diagnosis of rectal CT during the study period of which 173 (29.7%) were known to be HIV positive. 118 MSM (20.2%; 64 HIV negative; 54 HIV positive) underwent additional testing for LGV and 32 infections (26 HIV positive MSM) were confirmed. All asymptomatic LGV infections (n = 5; 15.6%) were diagnosed in HIV positive MSM whilst all HIV negative MSM with LGV infection were symptomatic.

Discussion/conclusion We report a higher incidence of asymptomatic LGV infection in MSM than previously reported. Whilst the number of confirmed LGV infections is low, results suggest screening for LGV infection may be appropriate in all HIV positive MSM with confirmed rectal CT regardless of symptomatology.

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