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P09.05 Unusually low prevalence of mycoplasma genitalium and trichomonas vaginalis in urine samples from chinese women attending a centre of prenatal diagnosis
  1. Yan Han1,
  2. Minjian Chen2,3,
  3. Yueping Yin1,
  4. Yankai Xia2,3,
  5. Xiangsheng Chen1
  1. 1National Center for STD Control & Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Dermatology, Nanjing, China
  2. 2State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing 210029, China
  3. 3Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 210029, China

Abstract

Introduction Sexually transmitted infections (STIs) in pregnant women are health problems that lead to serious medical complications and consequences. This study aimed to investigate the prevalence of six STIs among pregnant women attending a centre of prenatal diagnosis.

Methods From Feb 2008 to Dec 2010, women who attending centre of prenatal diagnosis of Nanjing maternity and child health hospital seeking for medical care were enrolled in this study. A case-control study was conducted that 42 case women who suffered a medically unexplained spontaneous abortion and 159 control women who had no history of spontaneous abortion and had at least one living child. Six kinds of sexually transmitted infections such as Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, Mycoplasma hominis, and Ureaplasma urealyticum was detected by using the DiaPlexQTM STI-6 Detection Kit.

Results The overall prevalence of any STI was 11.90% in case women while 16.98% in control women. Mycoplasma genitalium and Trichomonas vaginalis were not found in case women and these in 0.63% control women. Chlamydia trachomatis and Ureaplasma urealyticum were detected in 4.76% and 11.90% of case women which were higher than these in control women; None Neisseria gonorrhoeae were found in case women while in 4.40% control samples. Mycoplasma hominis were 2.38% in case and 9.43% in control. The lack of association between STIs and spontaneous abortion was found in this study.

Conclusion Comparison with reported data, unusually low prevalence of Mycoplasma genitalium and Trichomonas vaginalis were found in Chinese women attending a centre of prenatal diagnosis who residing in the middle and lower reaches of the Yangtze River. While screening all pregnant women with these STI-6 PCR method will save a lot of time, the Chinese Mycoplasma genitalium and Trichomonas vaginalis prevalence remains low and this STI-6 Detection Kit is unlikely to be cost effective.

Disclosure of interest statement The Australasian Society for HIV Medicine recognises the considerable contribution that industry partners make to professional and research activities. We also recognise the need for transparency of disclosure of potential conflicts of interest by acknowledging these relationships in publications and presentations.

No pharmaceutical grants were received in the development of this study.

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