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P16.10 Worsen epidemic of early hiv infection among men who have sex with men in china: implication for real time action
  1. W Tang1,2,
  2. J Xu3,4,
  3. H Zou5,
  4. T Mahapatra6,
  5. Q Hu1,2,
  6. G Fu7,
  7. Z Wang8,
  8. L Lu9,
  9. M Zhuang10,
  10. X Chen11,
  11. J Fu12,
  12. Y Yu3,4,
  13. J Lu3,4,
  14. Y Jiang3,4,
  15. W Geng3,4,
  16. X Han3,4,
  17. H Shang3,4
  1. 1University of North Carolina at Chapel Hill, Project-China, No. 2 Lujing Road, Guangzhou, 510085, China
  2. 2Guangdong Provincial Center for Skin Diseases and STIs Control, Guangzhou, 510085, China
  3. 3Key Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, 110001, China
  4. 4Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China
  5. 5Kirby Institute, The University of New South Wales, Sydney, NSW, 2052, Australia
  6. 6Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles. Los Angeles, 90095, USA
  7. 7Jiangsu Provincial Centers for Disease Control and Prevention, Nanjing, China
  8. 8He’nan Provincial Centers for Disease Control and Prevention, Zhengzhou, China
  9. 9Yunnan Provincial Centers for Disease Control and Prevention, Kunming, China
  10. 10Shanghai Municipal Centers for Disease Control and Prevention, Shanghai, China
  11. 11Hu’nan Provincial Centers for Disease Control and Prevention, Changsha, China
  12. 12Shandong Provincial Centers for Disease Control and Prevention, Jinan, China

Abstract

Background Recent upsurge of new HIV infections among men who have sex with men (MSM) is a major concern in China. Paucity of national-level information regarding the burden and predictors of this progressive epidemic of new infections called for a multi-centric, timely and comprehensive investigation.

Methods Mixed methods were used to recruit MSM (MSM) from seven cities in China between 2012 and 2013. Early and established HIV infections were estimated by Western Blot and BED HIV-1 capture enzyme immunoassay. Syphilis and herpes simplex virus-2 (HSV-2) were also tested.

Results A total of 4496 eligible MSM were recruited. The majority was aged ≤35 years (77·5%), migrants (60·3%), never married (69·8%), and played receptive role in anal sex (70·5%). The HIV prevalence was 9·9%, and 41·9% were recently infected, with HIV incidence of 8·9/100 Person-Years (95% CI: 7·6–10·2). The prevalence of history HSV-2 and syphilis were 12·5% and 8·5%, respectively. Early HIV infection was associated with having multiple male partners (aOR = 1·4, 95% CI 1·1–1·9), recreational drug use (aOR = 2·2, 95% CI 1·6–3·0), anal bleeding (aOR = 2·1, 95% CI 1·4–3·0), circumcision experience (aOR = 2·0, 95% CI 1·3–3·1), syphilis infection (aOR = 2·8, 95% CI 1·9–4·3) and history HSV-2 infection (aOR = 2·3, 95% CI 1·5–3·3).

Conclusion High rate of early HIV infection is potentially resulting in progressive deterioration of the overall HIV epidemic among MSM in China. Targeted interventions to address high-risk MSM including those having multiple partners, history of recreational drug use and syphilis or HSV-2 infection seemed to be the need of the hour.

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