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P16.17 Correlation between demographics, clinical and risk factor for hiv infected with hiv/tb co-infected in amertha clinic kerti praja foundation bali
  1. ON Yuneti1,
  2. IWG Artawan Eka Putra1,2,
  3. AAS Sawitri1,3,
  4. DN Wirawan1,3,4
  1. 1Udayana University, Post Graduate School of Public Health, Bali, Indonesia
  2. 2Udayana University, School of Public Health Faculty of Medicine Bali, Indonesia
  3. 3Udayana University, Department of Community and Preventive Medicine Faculty of Medicine, Bali, Indonesia
  4. 4Kerti Praja Foundation Bali, Indonesia

Abstract

Introduction HIV infection increases the risk of developing Tuberculosis (TB), as TB infection increases the progression of HIV. In Indonesia, the rate of patients HIV positive with TB (HIV/TB co-infected) have reported 31.8% in 2013. In Bali HIV/TB co-infected patients have increased from 26% in 2012 to 30% in 2013. This study aims to determine the correlation between demographics, clinical and risk factor for HIV infected with HIV/TB co-infected in Amertha Clinic Kerti Praja Foundation Bali.

Methods A cross-sectional study using secondary data of patients with HIV/AIDS who were receiving antiretroviral therapy (ART) from 2002–2012. Independent variables were demographics: sex, age, education level, occupation, and presence of ART supervisor; clinical: haemoglobin count, weight, and CD4 count; and risk factor for HIV infected. The status of HIV/TB co-infection was the dependent variable. All variables are conditions of patients when starting receiving ART. Data was analysed using univariate, bivariate (chi-square) and multivariate (cox regression).

Results From the 531 patients, the majority were male (57,6%), aged ≥31 years (50,8%), and starting ART with median CD4 count 130 (IQR = 40–224) cell/mm3. We found 5,5% of patients experienced HIV/TB co-infection. In multivariate analysis, the variables was correlated with HIV/TB co-infection were a CD4 count at baseline ≤ 200 cell/mm3(PR = 10,34; 95% CI = 1,39–76,69) and patients with a history of injecting drugs compared to patients reporting heterosexual contact (PR = 3,27; 95% CI = 1,56–6,88).

Conclusion Patients with CD4 count ≤ 200 cell/mm3 and patients with a history of injecting drugs have correlating with HIV/TB co-infection. These data support national recommendations encouraging early initiation ART when CD4 counts is higher. These data also suggests that promote awareness and monitoring patients with low CD4 count and who have a history injecting drugs for the presence of HIV/TB co-infection, particularly in those patients whose sputum smear examination or radiology was negative for TB.

Disclosure of interest statement None.

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