Sex Transm Infect 92:87 doi:10.1136/sextrans-2016-052567
  • Whistlestop tour

Highlights from this issue

  1. Jackie A Cassell, Editor in Chief

Syphilis, has always been known the "protean" disease, capable of manifesting in many forms and deceiving physicians as to its true nature. It confused Hunter, whose inoculation experiments1 were the forerunner of the Tuskegee and Guatemala experiments2—it is disputed whether he experimented on himself, but not that he inoculated others in support of a unitary theory of gonorrhoea and syphilis. The huge impact of syphilis on pre-penicillin public health together with its place at the centre of moral debate, and the difficulty of diagnosis made it central to paradigm shifts in the philosophy of science as described in Fleck's seminal work “The Genesis and Development of a Scientific Fact”,3 first published in German in 1935. Many developed countries have seen a …