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P206 Prevalence and risk factors associated with chlamydia trachomatis (CT), mycoplasma genitalium (MG) and neisseria gonorrhoeae(NG): cross-sectional study in three sexual health clinics
  1. Claire Broad1,
  2. Emma Harding-Esch1,2,
  3. Mark Harrison1,
  4. Marcus Pond1,
  5. NgeeKeong Tan3,
  6. Clare Soares1,
  7. Sebastian Fuller1,
  8. Sandra Okala2,
  9. Syed Tariq Sadiq1,2
  1. 1St George’s University of London, London, UK
  2. 2Public Health England, London, UK
  3. 3St George’s University Hospitals NHS Foundation Trust, London, UK

Abstract

Introduction Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), and Neisseria gonorrhoeae (NG) infections contribute to major reproductive health sequelae. CT and NG are routinely tested for in sexual health clinics (SHCs), whereas MG is not. Population prevalence estimates for males and females for CT and MG are >1% and <0.1% for NG infection. Risk factor data, which help target control interventions, are limited in men-who-have-sex-with-men (MSM). We assessed prevalence and risk factor data in symptomatic patients accessing SHCs.

Methods Patients aged ≥16 years with symptoms of an STI provided: vulvovaginal swabs (females), first void urine (men-who-have-sex-with-women (MSW) and MSM) and pharyngeal and rectal swabs (MSM). Routine clinic results were obtained and FTD Urethritis Plus kit used to detect MG. Risk factors (RFs) were analysed using univariate (UV) and multivariate (MV) logistic regression.

Results

Abstract P206 Table 1

Prevelance and risk factors associated with STIs

The only RFs associated with any organism in MV analyses was in females. Being aged 16–19, a contact of someone with an STI, and not bleeding were associated with CT and being a contact was the only RF for NG.

Discussion CT and MG positivity were highest in MSW compared with other patient groups, whereas NG positivity was highest in MSM, especially rectal samples. In the absence of routine MG testing, NG-positive MSM would be treated with 1 g azithromycin, (combined with 500 mg ceftriaxone) which could result in MG antimicrobial resistance development. From our study population, with no RFs for CT, NG or MG, a targeted test and treat approach would not be beneficial in MSW or MSM.

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