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The Influence of Epidemic Phase on the Cost- Effectiveness of an STI Prevention Intervention: An exploratory analysis
  1. Harrell W. Chesson (hbc7{at}
  1. Centers for Disease Control and Prevention, United States
    1. Peter J White (p.white{at}
    1. Imperial College, United Kingdom


      Objectives: To explore how the cost-effectiveness of a behavior-change STI prevention program varies with the phase of an STI epidemic.

      Methods: We used a model of STI transmission and standard methods of cost-effectiveness analysis to examine the cost-effectiveness of a hypothetical, behavior-change intervention initiated at various phases of an STI epidemic.

      Results: The intervention was more cost-effective when initiated in earlier phases of the epidemic rather than later phases, under a range of scenarios. However, the relative impact of the timing of the initiation of the STI prevention intervention on the cost- effectiveness was quite minor compared to other important factors, such as the cost and impact of the intervention and the lifetime medical cost of the STI.

      Conclusions: Earlier initiation of an intervention can improve the cost-effectiveness of the intervention, although this result does not hold for all possible scenarios.

      • cost-effectiveness
      • prevention
      • sexually transmitted diseases

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