Objective: In Japan, it was reported that about 9 % of sexually active female teenagers had Chlamydia trachomatis. Most of them were asymptomatic which may lead to continuing spread of the infection. Mycoplasma genitalium is also a pathogen in male non-gonococcal urethritis. However, few studies of the prevalence of M. genitalium in the general population have been reported. The objective of this study was to determine the prevalence of M. genitalium infection among younger females and to determine risk factors for this infection.
Methods: The study was conducted between October 2005 and January 2006, using first voided urine specimens and questionnaires from female students of 3 vocational schools in the Miyazaki prefecture, Japan. C. trachomatis was detected with Amplicor™ PCR. M. genitalium was detected with inhibitor controlled real-time TaqManTM PCR detecting the MgPa adhesion gene and with a PCR detecting the 16S rRNA. Risk factors associated with infection of M. genitalium or C. trachomatis were analyzed with Fisher's exact test.
Results: Among 298 female, 249 (84%) had had experience of sexual intercourse. The prevalence of M. genitalium was 2.8% (95% CI: 0.76%-4.86%), the corresponding prevalence of C. trachomatis was 8.8% (95% CI: 5.31%-12.36%). Two risk factors for M. genitalium infection were identified; these were more than 5 life-time partners and co-infection with C. trachomatis.
Conclusion: The prevalence of M. genitalium was 2.8% in female students in Japan. The risk factors of infection with M. genitalium were more than 5 lifetime sexual partners and co-infection with C. trachomatis.
- Chlamydia trachomatis
- Mycoplasma genitalium
- female students