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Syphilis is a spirochetal infection with multiple manifestations. In recent years, syphilis has re-emerged as a significant public health problem in many countries including China.1 However, the factors that predict serological response after syphilis treatment have not been well-defined.
We performed a retrospective study of patients who were diagnosed as having early syphilis in our clinic between the years 2000 and 2010. Analysis of factors determining the serological response to treatment was performed in HIV-negative patients with early syphilis, using demographic characteristics, clinical characteristics (i.e., sex, age, residence, coinfection with other STDs, …