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PCR detection in diagnosis of early syphilis: a preliminary result from China
  1. Rui-Rui Peng1,2,
  2. Yue-Ping Yin1,3,
  3. Wan-Hui Wei1,3,
  4. Hong-Chun Wang1,3,
  5. Jin-Ping Zhang1,
  6. Xiang-Sheng Chen1,3
  1. 1Institute of Dermatology of Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China
  2. 2Shanghai Skin Disease Hospital, Shanghai, China
  3. 3National Center for STD Control, Nanjing, China
  1. Correspondence to Dr Xiang-Sheng Chen, National Center for STD Control, 12 Jiangwangmiao Street, Nanjing 210042, China; chenxs{at}ncstdlc.org

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Recently, Gayet-Ageron and colleagues published a systematic review and meta-analysis to evaluate the diagnostic values of Treponema pallidum PCR and concluded that PCR is a useful additional diagnostic tool.1 However, the data on examining diagnostic performance of PCR-based methods for early syphilis are still limited in China although a few studies with the indirect data from China were included in the literature review.1

During April to September 2009, we conducted a survey among patients with suspected primary or secondary syphilis recruited from an STI clinic in Nanjing, China, to evaluate the performance of PCR assay for early syphilis diagnosis. Following an ethical review by …

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