Adult urologyPrevalence of chronic prostatitis in men with premature ejaculation☆
Section snippets
Patients
A total of 46 consecutive heterosexual men aged 18 to 68 years (mean age 41.2 ± 12.3; group A, 18 to 30 years, n = 11; group B, 31 to 50 years, n = 25; and group C, 51 to 68 years, n = 12) with premature ejaculation (21 with PPE, mean age 40.1 ± 14.1 years and 25 with SPE, mean age 42.1 ± 10.7 years) were recruited from our Andrology Unit. An age-matched group of 30 healthy volunteers (age range 23 to 61 years; mean age 39.6 ± 9.3) divided into three groups of 10 men each by age (23 to 30, 31
Results
In the 46 patients with premature ejaculation, 13 (28.2%) exhibited one or more clinical symptoms of prostatitis. Twenty-six patients (56.5%) had 10 or more white blood cells per high power field in their expressed prostatic secretions; four of these patients had culture-negative results in all three specimens of urine and prostatic fluid and were considered to have nonbacterial prostatitis. The results of the microbiologic investigations showed prostatic infection in 22 (47.8%) of the 46
Comment
The results of this study demonstrated a high prevalence of chronic prostatitis in patients with premature ejaculation compared with an age-matched control group and suggest that prostatic infection and/or inflammation is a predisposing condition for premature ejaculation. According to the classification proposed by Drach et al.,24 22 of our cohort of 46 subjects demonstrated chronic bacterial prostatitis, 4 had chronic nonbacterial prostatitis, and none was affected by prostatodynia.
In early
Conclusions
If larger studies confirm our findings, a routine examination of the prostate in the clinical evaluation of patients with premature ejaculation should be performed. The bacteriologic localization test, as described by Meares and Stamey,23 even in the absence of symptoms, should be performed before considering psychosexual or pharmacologic therapies for this sexual disorder.
Acknowledgements
To Massimino D’Armiento, M.D. and Susanna Dolci, M.D. for critical reading of the manuscript; to Paola Minelli and Daniela Di Gregorio for their secretarial work; and to Rosaria Caruso, M.D. for adapting her English expertise to our needs.
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This study was partially supported by MURST grants.