Abstract
In a randomised, double-blind comparison of a maternal short regimen of oral zidovudine with placebo in West Africa the 15-month efficacy of zidovudine in preventing mother-to-child transmission of HIV-1 infection was estimated at 30% (95% CI -2 to 52).
Publication types
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Clinical Trial
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Clinical Trial, Phase II
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Clinical Trial, Phase III
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Letter
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Anti-HIV Agents / administration & dosage*
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Anti-HIV Agents / adverse effects
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Breast Feeding*
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Burkina Faso
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Cote d'Ivoire
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Double-Blind Method
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Female
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Follow-Up Studies
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HIV Infections / drug therapy
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HIV Infections / prevention & control
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HIV Infections / transmission*
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HIV-1 / drug effects*
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Humans
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Infant
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Infant, Newborn
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Infectious Disease Transmission, Vertical*
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Pregnancy
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Pregnancy Complications, Infectious / drug therapy*
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Treatment Outcome
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Zidovudine / administration & dosage*
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Zidovudine / adverse effects
Substances
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Anti-HIV Agents
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Zidovudine