Mycoplasma genitalium is not associated with adverse outcomes of pregnancy in Guinea-Bissau

Sex Transm Infect. 2002 Aug;78(4):289-91. doi: 10.1136/sti.78.4.289.

Abstract

Objective: To evaluate the impact of Mycoplasma genitalium on the outcome of pregnancy.

Methods: Cervical samples from women who had previously participated in a case-control study (designed to assess the impact of syphilis and HIV-2 on the outcome of pregnancy in Guinea-Bissau) were processed using a PCR assay to detect the presence of M genitalium. Controls were women who had delivered a term neonate with a birth weight over 2500 g. Cases were classified into four groups of mothers according to the outcome of pregnancy: stillbirths, spontaneous abortions, premature deliveries, and small for gestational age (SGA) babies.

Results: Among the 1014 women included in this study, 6.2% were infected with M genitalium. M genitalium infection was not significantly associated with any of the adverse outcomes of pregnancy studied. Odds ratios (OR) for premature or SGA delivery in the presence of M genitalium infection were 1.37 (95% CI 0.69 to 2.60) and 0.44 (95% CI 0.01 to 2.75), respectively. For abortions and stillbirths, OR were respectively 0.61 (95% CI 0.07 to 2.51) and 1.07 (95% CI 0.42 to 2.42).

Conclusion: M genitalium appears not to have a deleterious impact on the outcome of pregnancy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Chi-Square Distribution
  • Female
  • Guinea-Bissau / epidemiology
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Mycoplasma Infections / complications*
  • Mycoplasma Infections / epidemiology
  • Mycoplasma hominis / isolation & purification
  • Parity
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / microbiology*
  • Pregnancy Outcome
  • Prevalence
  • Uterine Cervical Diseases / microbiology*