Genital ulcers in Kenya. Clinical and laboratory study

Br J Vener Dis. 1981 Dec;57(6):378-81. doi: 10.1136/sti.57.6.378.

Abstract

Of 97 patients with genital ulcers attending a special treatment clinic in Nairobi, Kenya, 60 harboured Haemophilus ducreyi, four herpes simplex virus, and five Neisseria gonorrhoeae. Eleven patients had serological evidence of syphilis; of these one case was confirmed by darkfield microscopy. In the remaining cases no aetiological agent was identified. An enriched chocolate agar with vancomycin and serum was a useful medium for primary isolation of H ducreyi. Tetracycline was generally ineffective in the treatment of ulcers, but sulfadimidine was successful in almost 80% of cases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chancroid / drug therapy
  • Female
  • Genital Diseases, Male / microbiology*
  • Haemophilus ducreyi / isolation & purification
  • Humans
  • Kenya
  • Male
  • Neisseria gonorrhoeae / isolation & purification
  • Sulfamethazine / therapeutic use
  • Tetracycline / therapeutic use
  • Ulcer / microbiology*

Substances

  • Sulfamethazine
  • Tetracycline