Table 2

20% Podophyllin versus 0.15–0.5% podophyllotoxin

PodophyllinPodophyllotoxin
Non-standardised, unstableStandardised, stable
Local toxicity highLocal toxicity low
Systemic toxicity highSystemic toxicity negligible
Teratogenic and fetotoxicNon-teratogenic
High mutagenicityNo mutagenicity
Carcinogen effect?No carcinogen effect
Low efficacyHigh efficacy
Clinic treatmentSelf treatment
High treatment costModerate treatment cost