Demographic, drug history, and number with abnormal lipids in patients taking protease inhibitors (PI), non-nucleoside reverse transcription inhibitors (NNRTI), and naive to antiretroviral therapy. Details of nucleoside analogues (NRTI) taken by the patient at any time in their life for >1 month are also given
| PI (n=57) | NNRTI (n=17) | Naive (n=50) | |
|---|---|---|---|
| HAART = patients taking three or more antiviral drugs. | |||
| *Not all patients had lipoprotein(a) measurement. | |||
| Median age (range) | 40 (23–56) | 38 (19–66) | 38 (19–65) |
| White | 51 | 11 | 40 |
| Women | 9 | 3 | 9 |
| Homosexual | 44 | 9 | 34 |
| Months on HAART (range) | 12.5 (1–29) | 9 (1–19) | — |
| NRTI | |||
| AZT | 51 | 15 | |
| D4T | 38 | 4 | |
| 3TC | 48 | 15 | |
| ddI | 34 | 3 | |
| ddC | 1 | ||
| Dyslipidaemia (number) | |||
| Cholesterol >6.5 mmol/l | 30 | 1 | 1 |
| HDL cholesterol <0.9 mmol/l | 9 | 4 | 17 |
| Triglyceride >2.3 mmol/l | 37 | 3 | 10 |
| Lipoprotein(a) >300 mg/l | 19/50* | 7 | 8/24* |