Demographic and behavioural associations with HSV-1 antibody prevalence, with unadjusted odds ratios (ORs) based in all participants and adjusted ORs based on sexually active participants only
| GUM attenders | Blood donors | |||||
|---|---|---|---|---|---|---|
| Characteristic | HSV-1 prevalence, % (No HSV-1 +ve) | p Value, unadjusted OR | p Value, adjusted OR | HSV-1 prevalence, % (No HSV-1 +ve) | p Value, unadjusted OR | p Value, adjusted OR |
| *For these ordinal factors, statistical tests are based on the raw figures, not the grouped data. The Mann-Whitney test is used for the unadjusted testing, and the adjusted is based on the inclusion of the linear term in the logistic regression model. | ||||||
| Sex | p=0.35 | p=0.13 | ||||
| Female | 47 (678) | 1 – | 1 – | |||
| Male | 45 (329) | 0.91 (0.73–1.12) | 0.83 (0.65–1.06) | |||
| Sex/orientation | p=0.001 | p=0.005 | ||||
| Female | 58 (199) | 1 – | 1 – | |||
| Male heterosexual | 56 (162) | 0.91 (0.66–1.25) | 0.66 (0.46–0.95) | |||
| Male homosexual | 72 (138) | 1.82 (1.24–2.65) | 1.36 (0.83–2.23) | |||
| Age* | p<0.001 | p<0.001 | p<0.001 | p<0.001 | ||
| ≤24 | 53 (127) | 1 – | 1 – | 39 (80) | 1 – | 1 – |
| 25–34 | 60 (258) | 1.37 (1.00–1.88) | 1.50 (1.03–2.18) | 41 (219) | 1.09 (0.78–1.51) | 1.00 (0.67–1.49) |
| 35–44 | 69 (80) | 1.99 (1.25–3.18) | 2.65 (1.49–4.72) | 50 (186) | 1.59 (1.12–2.24) | 1.47 (0.94–2.30) |
| 45+ | 79 (34) | 3.39 (1.57–7.38) | 3.61 (1.43–9.14) | 56 (166) | 2.06 (1.43–2.96) | 2.07 (1.27–3.39) |
| Ethnicity | p=0.001 | P=0.001 | p=0.43 | p=0.64 | ||
| White | 58 (404) | 1 – | 1 – | 46 (602) | 1 – | 1 – |
| Black | 80 (66) | 2.97 (1.69–5.24) | 3.34 (1.83–6.11) | 54 (27) | 1.40 (0.80–2.47) | 1.53 (0.78–2.99) |
| Asian | 58 (18) | 1.00 (0.48–2.07) | 1.10 (0.49–2.48) | 50 (10) | 1.20 (0.49–2.89) | 0.99 (0.30–3.22) |
| Other | 54 (7) | 0.84 (0.28–2.53) | 0.70 (0.22–2.27) | 62 (8) | 1.91 (0.62–5.88) | 1.30 (0.34–4.98) |
| Occupation class | p=0.02 | p=0.05 | ||||
| I–III | 58 (365) | 0.66 (0.47–0.93) | 0.68 (0.46–1.00) | |||
| Other | 68 (128) | 1 – | 1 – | |||
| Marital status | p=0.22 | p=0.47 | p<0.001 | p=0.03 | ||
| Single | 59 (312) | 0.83 (0.62–1.12) | 0.88 (0.63–1.24) | 39 (240) | 0.61 (0.49–0.76) | 0.73 (0.55–0.97) |
| Other | 63 (185) | 1 – | 1 – | 51 (408) | 1 – | 1 – |
| Lifetime sexual partners* | p=0.002 | p=0.13 | ||||
| 1–9 | 53 (148) | 1 – | 1 – | |||
| 10–19 | 58 (111) | 1.21 (0.83–1.75) | 1.13 (0.75–1.71) | |||
| 20–49 | 55 (101) | 1.08 (0.74–1.56) | 0.88 (0.56–1.39) | |||
| 50+ | 77 (97) | 2.92 (1.81–4.70) | 1.85 (1.00–3.39) | |||
| p=0.03 | p=0.21 | |||||
| 0 | 36 (28) | 1 – | – | |||
| 1–4 | 44 (260) | 1.42 (0.87–2.31) | 1 – | |||
| 5–9 | 51 (163) | 1.83 (1.10–3.05) | 1.29 (0.96–1.73) | |||
| 10+ | 48 (123) | 1.62 (0.96–2.74) | 1.07 (0.77–1.49) | |||
| Age at first sexual intercourse* | p=0.003 | p=0.003 | p=0.01 | p=0.001 | ||
| ≤15 | 72 (120) | 1 – | 1 – | 50 (65) | 1 – | 1 – |
| 16–17 | 58 (169) | 0.54 (0.36–0.82) | 0.59 (0.37–0.92) | 51 (179) | 1.04 (0.70–1.56) | 0.94 (0.59–1.49) |
| 18–19 | 56 (117) | 0.49 (0.32–0.76) | 0.45 (0.28–0.74) | 45 (180) | 0.82 (0.55–1.22) | 0.77 (0.49–1.22) |
| 20+ | 56 (83) | 0.49 (0.31–0.79) | 0.37 (0.21–0.65) | 44 (194) | 0.80 (0.54–1.18) | 0.64 (0.39–1.05) |
| Not yet | – | – | – | 36 (28) | 0.56 (0.31–1.00) | – |