Probability of infection following a positive test, % | Probability of infection following a negative test result, % | |||||||
---|---|---|---|---|---|---|---|---|
Study | Risk group | Pretest probability of infection, % | Test 1 | Test 2 | Test 3 | Test 1 | Test 2 | Test 3 |
*The sensitivity/specificity (%) of tests 1, 2, and 3 are 92/98, 95/98, and 98/98 respectively. | ||||||||
1 | Lowest | 0.7 | 24.5 | 25.1 | 25.7 | 0.06 | 0.04 | 0.01 |
Highest | 47.3 | 97.6 | 97.7 | 97.8 | 6.8 | 4.4 | 1.8 | |
2 | Lowest | 4.1 | 66.3 | 67.0 | 67.7 | 0.34 | 0.22 | 0.09 |
Highest | 67.7 | 99.0 | 99.0 | 99.0 | 14.6 | 9.7 | 4.1 | |
3 | Lowest | 4.8 | 69.9 | 70.5 | 71.2 | 0.41 | 0.26 | 0.10 |
Highest | 53.3 | 98.1 | 98.2 | 98.2 | 8.5 | 5.5 | 2.3 | |
4 | Lowest | 2.7 | 56.1 | 56.9 | 57.6 | 0.23 | 0.14 | 0.06 |
Highest | 63.9 | 98.8 | 98.8 | 98.9 | 12.6 | 8.3 | 3.5 |