Range of sensitivity and specificity values for H ducreyi diagnostic tests
| Diagnostic test | Sensitivity (%) | Specificity (%) | Reference standard | References |
|---|---|---|---|---|
| PCR = polymerase chain reaction, IF = immunofluorescence, EIA = enzyme immunoassay, LOS = lipo-oligosaccharide. | ||||
| Microscopy | 5–36 | not stated | clinical diagnosis | 56, 57 |
| 10–63 | 51–99 | culture | 56, 58, 59 | |
| Culture | 61–91 | not stated | clinical diagnosis | 27, 28 |
| 35–75 | 94–100 | PCR | 19, 34, 37, 40 | |
| PCR | 83–96 | 100 | clinical diagnosis | 36, 38 |
| 56–100 | 52–100 | culture | 34, 38, 40 | |
| Antigen detection (IF) | 93–100 | 63–74 | culture | 41, 42 |
| 89 | 81 | PCR | 42 | |
| Non-adsorption EIA | 55–89 | 49–96 | culture | 47 |
| Adsorption EIA | 81–100 | 23–88 | culture | 48 |
| 53–83 | 57–71 | PCR | 51, 60 | |
| LOS EIA | 83–96 | 97 | culture | 42, 49 |
| 48–74 | 89–90 | PCR | 42, 51, 60 | |