Failure rates of standard and alternative treatment regimens 1 week after completion of treatment
| Treatment regimen | Failure rate (%) |
|---|---|
| Standard regimens | |
| Ceftriaxone 125 mg intramuscularly + doxycycline 100 mg orally twice daily for 7 days | 69 |
| Ciprofloxacin 500 mg + doxycycline 100 mg twice daily for 7 days | 93 |
| Ofloxacin 400 mg + doxycycline 100 mg twice daily for 7 days | 90 |
| Alternative regimens | |
| 1 g ceftriaxone for 5–10 days + doxycycline 100 mg twice daily for 10 days | 48 |
| 500 mg ciprofloxacin twice daily for 7–14 days + doxycycline 100 mg twice daily for 10 days | 64 |
| 800 mg ofloxacin alone | 74 |
| Ceftizoxime 1–3 g 3 times daily + amikacin 500–1000 mg twice daily, + doxycycline 100 mg twice daily all for 7–10 days, ± metronidazole 500 mg 3 times daily for 7 days ± erythromycin 400 mg four times daily for 14 days | 18 |