Univariate correlates of cervicovaginal HIV-1 and HIV-2 shedding
| HIV-1 shedding | HIV-2 shedding | |||||||
|---|---|---|---|---|---|---|---|---|
| Variables | Positive (n=55) | Negative (n=152) | OR 95% CI | p Value* | Positive (n=10) | Negative (n=59) | OR 95% CI | p Value* |
| OR = odds ratio. | ||||||||
| CI = confidence interval. | ||||||||
| *χ2 test. | ||||||||
| ND = not done. | ||||||||
| Vaginal pH (mean) | 5.7 | 5.35 | <0.001 | 5.4 | 5.4 | 1.0 | ||
| Vaginal discharge | 45/53 | 104/150 | 2.2 (0.9–5.3) | 0.05 | 9/10 | 34/58 | 6.3 (0.7–14.3) | 0.06 |
| Genital ulceration | 24/55 | 38/149 | 2.2 (1.1–4.6) | 0.01 | 5/10 | 12/58 | 3.7 (0.7–19.3) | 0.06 |
| CD4 count <200 × 106/l | 27/45 | 35/135 | 4.1 (1.9–9.0) | <0.001 | 4/9 | 2/52 | 18.1 (2.1–24.8) | 0.003 |
| Plasma viral load >40 000 | 34/55 | 45/144 | 3.6 (1.8–7.2) | <0.001 | ND | ND | ||
| Serum vitamin A <0.07 μmol/l | 24/41 | 47/105 | 1.7 (0.8–3.9) | 0.13 | 7/18 | 15/47 | 4.8 (0.9–29.2) | 0.02 |
| AIDS clinical stage (stage C) | 28/53 | 17/131 | 6.01 (2.7–13.6) | <0.001 | 2/10 | 1/59 | 14.5 (0.6–869) | >0.05 |