Scenario data inputs, estimates of the average number of males infected with an STI by each infected woman during the delay in diagnosis and treatment (Y), and the required sensitivity of the POC test (Sr)
| Data inputs for scenarios considered | Results | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Scenario and data source | No of partners | No of sex acts per partner | Prevalence | Consistency of condom use | Average number of males infected per infected woman in 10 days’ delay in treatment (Y) | Required sensitivity of POC test (Sr) | |||
| GC among women | CT among women | CT | GC | CT | GC | ||||
| The range in parentheses gives the lower and upper estimates when the STI transmission probabilities and condom efficacy estimates are varied. It is assumed there is a 10 day delay in treatment when using the gold standard test, an 80% return rate, and that the gold standard tests for C trachomatis and N gonorrhoeae are 90% sensitive. | |||||||||
| CT = C trachomatis.; GC = N gonorrhoeae. | |||||||||
| No transmission during delay in treatment | NA | NA | NA | NA | NA | 0.00 | 0.00 | 72% | 76% |
| Sex workers to clients, 1997 (South Africa)17 | 2.3 per week | 1 per week | 17.3% | 14.3% | 3% of clients | 1.04 (0.69, 1.61) | 2.19 (1.64, 2.77) | 35% (28%, 42%) | 23% (19%, 27%) |
| Sex workers to clients, 1999 (Benin)16 | 10 per week | 1 per week | 20.5% | 5.1% | 60%–80% of clients | 0.66 (0.39, 1.16) | 1.74 (1.03, 3.08) | 43% (33%, 52%) | 26% (18%, 35%) |
| Sex workers attending outreach service at GUM clinic, 1993 (UK)20,21 | ∼6.8 per week | 1 per week | 3.0% | 8.2% | 90% | 0.18 (0.09, 0.33) | 0.54 (0.29, 0.95) | 61% (54%, 66%) | 47% (37%, 57%) |
| Women at GUM clinic, 1997 (UK)22,23 | 2 per year | 2.5 per week | 5% | 5% | ∼30% | 0.01 (0.01, 0.02) | 0.02 (0.02, 0.03) | 71% (71%, 71%) | 70% (70%, 71%) |
| Women with long term partnerships, 1994 (Tanzania)18,19 | 2 per year | 1 per week | 7.3% | 6.1% | 0% | 0.01 (0.01, 0.02) | 0.02 (0.02, 0.03) | 71% (71%, 72%) | 71% (70%, 71%) |