Table 2

Diagnostic test, screening test and selection bias adjustments for STD measured at basline in Rakai (Rk), Masaka (Mk), and Mwanza (Mw)

Diagnostic test adjustmentScreening test adjustment
Se (range)Sp (range)Se′pscreenSelection bias adjustment
Observed prevalence adjusted according to equation 1 if no screening test used, according to equation 2 when screening test used. For selection bias adjustments see text for details. M = male, F = female, NG = gonorrhoea, CT = Chlamydia, TV = trichomoniasis, HSV-2 = herpes simplex virus type 2, Se = sensitivity, Sp = specificity, Se′ = sensitivity of screening test, pscreen = prevalence of positive screening test, na = not applicable.
Rk, CTF: 86.6 (75–98.4)F: 100 (na)nanana
M: 87.5 (75–100)M: 100 (na)
Rk, NGF: 83.8 (50–94.7)F: 100 (na)nanana
M: 88.9 (na)M: 100 (na)
Rk, TVF: 79.0 (69.7–88.3)F: 100 (na)nanana
Rk, HSV-292 (na)100 (na)nana% sexually active
15–19 years F: 0.71
20–24 years F: 0.99
25–29 years F: 1
15–19 years M: 0.52
20–24 years M: 0.94
25–29 years M: 1
Mk, CTF: 86.6 (75–98.4)F: 100 (na)nanana
M: 87.5 (75–100)M: 100 (na)
Mk, NGF: 83.8 (50–94.7)F: 100 (na)nanana
M: 88.9 (na)M: 100 (na)
Mk, HSV-291 (na)93 (na)nana
Mw, CTF: 48.8 (22.2–65)F: 100 (na)F: naF: nana
M: 70.3 (58–82.6)M: 100 (na)M: 53.3M: 0.25
Mw, NGF: 74.2 (50–96.4)F: 99.8 (98.9–100)F: naF: nana
M: 83.3 (na)M: 100 (na)M: 87.5M: 0.25
Mw, TVF: 60.9 (36.4–85.3)F: 99.8 (99.5–100)nana
Mw, HSV-291 (na)93 (na)nan6