Association between quartiles of TNF-α, IL-1β, and IL-6 concentration in lavage samples and microbiological and clinical variables
| β* | SE* | p Value* | |
|---|---|---|---|
| *Standardised regression coefficient (β), standard error (SE), and p value as obtained by stepwise multiple regression analysis on categorical variables. Dependent variables were quartiles of IL-1β, TNF-α and IL-6 concentration in lavage samples. Independent variables were included as quartiles of plasma HIV-RNA concentration and CD4+ cell counts and quartiles of HIV-DNA, HIV-RNA transcripts, cell free HIV-RNA concentration in lavage samples. Vaginitis, squamous intraepithelial lesion, genital HPV infection, and antiretroviral treatment were inserted as dichotomous variables. | |||
| TNF-α F | |||
| HIV-RNA transcripts (lavage) | 0.29 | 0.146 | 0.047 |
| Cell free HIV-RNA (lavage) | −0.37 | 0.148 | 0.012 |
| Antiretroviral treatment | −0.301 | 0.124 | 0.015 |
| IL-1β | |||
| HIV-DNA (lavage) | 0.383 | 0.16 | 0.017 |
| SIL | 0.23 | 0.115 | 0.045 |
| IL-6 | |||
| HIV-RNA transcripts (lavage) | 0.52 | 0.187 | 0.005 |
| Antiretroviral treatment | 0.23 | 0.11 | 0.037 |
| Vaginitis | −0.224 | 0.113 | 0.05 |