Time (h) for which free drug concentrations exceed summary MIC parameters (fT>MIC) for the most used cephalosporin regimens in gonorrhoea
| Cefuroxime | Ceftriaxone | Cefixime | ||||
|---|---|---|---|---|---|---|
| 200 mg oral | 1 g oral | 1.5 g intramuscular | 250 mg intramuscular | 500 mg intramuscular | 400 mg oral | |
| MIC50 | 9.6 | 12.6 | 13.9 | 57.9 | 66.4 | 29.2 |
| MIC90 | 6.8 | 10.0 | 11.2 | 41.0 | 49.5 | 22.4 |
| MICmax | 0.0 | 0.0 | 4.6 | 15.0 | 23.6 | 18.8 |