Univariate analyses of HSV-2 seroprevalence of REACH III cohort by sex†
| Females (n = 230) | Males (n = 313) | |||||
|---|---|---|---|---|---|---|
| No | % positive (n)††§ | Crude OR (95% CI) | No | % positive (n)††§ | Crude OR (95% CI) | |
| *<0.05 **<0.01 ***<0.001. | ||||||
| †Only those variables that were significant (p<0.05) for one or other of the sexes are shown. | ||||||
| ‡Except for continuous variables which are expressed as median and interquartile range among positives and negatives. | ||||||
| §Denominator may vary from column totals owing to missing data, refusals to answer specific questions or skip patterns. | ||||||
| ¶In the previous 6 months. | ||||||
| ††p value calculated by χ2 or Fisher’s exact test for categorical variables and by Mann-Whitney two sample statistic for continuous variables. | ||||||
| ‡‡OR expresses the increase in odds associated with a 1 year increase. | ||||||
| Median age | ||||||
| Among positives | – | 26 (23–28)*** | 1.2 (1.1 to 1.3)‡‡ | – | 26 (23–28)*** | 1.2 (1.1 to 1.3)‡‡ |
| Among negatives | – | 22 (19–26) | – | 24 (20–27) | ||
| Race | ||||||
| African-American | 111 | 78.4 (87)*** | 5.5 (3.1 to 9.8) | 103 | 35.3 (36)*** | 3.1 (1.8 to 5.4) |
| Other | 0 | – | – | 11 | 27.3 (3) | 2.1 (0.5 to 8.5) |
| White | 118 | 39.8 (47) | 1.0 | 195 | 15.0 (30) | 1.0 |
| Injection drug user | ||||||
| Yes | 159 | 58.5 (93) | 1.0 (0.6 to 1.7) | 237 | 21.9 (52) | 1.0 (0.5 to 1.8) |
| No | 71 | 59.2 (42) | 1.0 | 76 | 22.4 (17) | 1.0 |
| Regular employment¶ | ||||||
| Yes | 65 | 4.6 (3)* | 0.5 (0.3 to 0.9) | 178 | 18.5 (33) | 0.6 (0.4 to 1.1) |
| No | 164 | 64.0 (105) | 1.0 | 135 | 26.7 (36) | 1.0 |
| Number of lifetime opposite sex partners | ||||||
| <10 | 114 | 52.6 (60) | 1.0 | 84 | 30.8 (33)** | 1.0 |
| 10–30 | 64 | 57.8 (37) | 1.2 (0.7 to 2.3) | 106 | 18.9 (20) | 1.5 (0.7 to 3.4) |
| 30+ | 36 | 75.0 (27) | 2.7 (1.2 to 6.3) | 107 | 13.1 (11) | 3.0 (1.4 to 6.3) |
| Same sex relationship ever | ||||||
| Yes | 59 | 64.4 (38) | 1.4 (0.8 to 2.6) | 10 | 50.0 (5)* | 3.7 (1.0 to 13.2) |
| No | 170 | 56.5 (96) | 1.0 | 302 | 21.2 (64) | 1.0 |
| Traded sex¶ | ||||||
| Yes | 59 | 81.0 (47)** | 3.9 (1.9 to 8.1) | 9 | 33.3 (3) | 1.7 (0.4 to 7.3) |
| No | 169 | 52.1 (88) | 1.0 | 301 | 21.9 (66) | 1.0 |
| Ever incarcerated | ||||||
| Yes | 136 | 65.4 (89)* | 1.9 (1.1 to 3.3) | 107 | 25.7 (61)** | 2.8 (1.3 to 6.2) |
| No | 93 | 49.5 (46) | 1.0 | 73 | 11.0 (8) | 1.0 |
| Previous gonorrhoea infection | ||||||
| Yes | 26 | 92.3 (24)*** | 10.1 (2.3 to 44.1) | 28 | 42.9 (12)** | 3.1 (1.4 to 6.8) |
| No | 203 | 54.2 (110) | 1.0 | 284 | 19.7 (56) | 1.0 |
| Previous chlamydia infection | ||||||
| Yes | 30 | 66.7 (20) | 1.5 (0.7 to 3.4) | 21 | 52.4 (11)** | 1.2 (0.8 to 1.9) |
| No | 199 | 57.3 (114) | 1.0 | 289 | 19.4 (56) | 1.0 |
| Previous syphilis infection | ||||||
| Yes | 9 | 100 (9)** | – | 2 | 50.0 (1) | 3.6 (0.2 to 58.8) |
| No | 220 | 56.8 (125) | 310 | 21.6 (67) | 1.0 | |
| Current HIV infection | ||||||
| Yes | 15 | 93.3 (14)** | 10.9 (1.4 to 84.2) | 9 | 77.8 (7)*** | 13.7 (2.8 to 67.4) |
| No | 215 | 56.3 (121) | 1.0 | 304 | 20.4 (62) | 1.0 |
| Sex partner ever injected drugs¶ | ||||||
| Yes | 76 | 42.1 (32)** | 0.4 (0.2 to 0.7) | 77 | 23.4 (18) | 1.0 (0.5 to 1.9) |
| No | 125 | 64.0 (80) | 1.0 | 183 | 23.0 (42) | 1.0 |
| Daily use of pot¶ | ||||||
| Yes | 29 | 34.5 (10)** | 0.3 (0.1 to 0.7) | 46 | 15.2 (7) | 0.6 (0.3 to 1.4) |
| No | 194 | 62.1 (121) | 1.0 | 262 | 22.9 (60) | 1.0 |
| Daily use of heroin and cocaine together¶ | ||||||
| Yes | 38 | 76.3 (29)* | 2.6 (1.1 to 5.7) | 39 | 28.2 (11) | 1.5 (0.7 to 3.2) |
| No | 190 | 55.8 (106) | 1.0 | 271 | 21.0 (57) | 1.0 |
| Daily heroin use¶ | ||||||
| Yes | 165 | 63.0 (104)* | 1.8 (1.0 to 3.3) | 232 | 22.0 (51) | 0.8 (0.5 to 1.8) |
| No | 64 | 48.4 (31) | 1.0 | 79 | 22.8 (18) | 1.0 |
| Years since debut of hard drug use‡‡ | ||||||
| Among positives | – | 4 (3–7)* | 1.1 (1.0 to 1.2) | – | 5 (3 to 8) | 1.1 (1.0 to 1.2) |
| Among negatives | – | 4 (2–5) | 1.0 | – | 5 (3 to 7) | 1.0 |
| Has sold drugs¶ | ||||||
| Yes | 49 | 83.7 (41)*** | 4.6 (2.1 to 10.4) | 117 | 24.8 (29) | 1.3 (0.7 to 2.2) |
| No | 179 | 52.5 (94) | 1.0 | 195 | 20.5 (40) | 1.0 |