Baseline characteristics and viral loads of cases and controls
| Urethritis | Controls | P Value** | |
|---|---|---|---|
| GU: gonococcal urethritis; CU: chlamydial urethritis; NSU: non-specific urethritis; BPVL: mean log10 blood plasma viral loads; SPVL: mean log10 semen plasma viral loads. | |||
| *Figures quoted are number of measurements/number of patients: **p value from comparison with controls. | |||
| Number | 20 (9 GU, 1 GU/CU, 3 CU, 7 NSU) | 35 | – |
| Median age (years) (range) | 33.3 (23.9–48.5) | 35.6 (24.5–61.8) | 0.345 |
| Years since HIV diagnosis (range) | 3.36 (0.41–14.18) | 1.13 (0.11–16.19) | 0.069 |
| White ethnicity (n) | 18 | 31 | 1.00 |
| Median partners in last 3 months (range) | 4 (1–21) | 3 (0–51) | 0.297 |
| Mean pre-study log10 BPVL (95% CI) | 4.26 (3.90 to 4.62) | 4.34 (4.06 to 4.63) | 0.728 |
| Median pre-study CD4 count (range) | 475 (56–1220) | 477 (44–1590) | 0.937 |
| BPVL at study visit 1 | |||
| All urethritis | 4.11 (3.76 to 4.45) | 4.21 (4.03 to 4.40) | 0.550 |
| GU/CU only | 4.17 (3.75 to 4.59) | – | 0.821 |
| NSU only | 4.00 (3.22 to 4.77) | – | 0.385 |
| BPVL after study visit 1 | |||
| All urethritis | 4.19 (3.78 to 4.59) (n = 22/15*) | 4.27 (4.02 to 4.52) (n = 23/21*) | 0.752 |
| GU/CU only | 4.38 (3.90 to 4.87) (n = 13/9*) | – | 0.657 |
| NSU only | 3.92 (3.24 to 4.60) (n = 9/6*) | – | 0.306 |
| SPVL at study visit 1 | |||
| All urethritis | 3.99 (3.53 to 4.45) | 3.55 (3.27 to 3.83) | 0.078 |
| GU/CU only | 4.27 (3.66 to 4.87) | – | 0.014 |
| NSU only | 3.48 (2.78 to 4.17) | – | 0.820 |
| SPVL after study visit 1 | |||
| All urethritis | 3.88 (3.54 to 4.23) (n = 21/16*) | 3.59 (3.24 to 3.94) (n = 24/23*) | 0.228 |
| GU/CU only | 4.12 (3.54 to 4.69) (n = 12/10*) | – | 0.111 |
| NSU only | 3.52 (3.39 to 3.66) (n = 9/6*) | – | 0.823 |