| Syndrome | Treatment regimen | Curable STI aetiology | n | Percentage cured | Reference | |
| Clinical % (n) | Microbiological % (n) | |||||
| Urethritis | 500 mg single dose ciprofloxacin since 2001 (250 mg before 2001) and 200 mg of doxycycline daily for 7 days | NG | 135 | 100 (135) | 100 (135) | 13 |
| CT | 24 | 100 (24) | 83 (20) | |||
| Ulcer | One intramuscular injection of 2.4 million units of penicillin and 500 mg dose of erythromycin 4 times daily for 5 days. | TP | 28 | 89 (25) | 14 | |
| No treatment for HSV-2 | HD | 30 | 93 (28) | |||
| CT (LGV) | 29 | 93 (27) | ||||
| Vaginal discharge | 500 mg single dose ciprofloxacin and 100 mg of doxycycline 2× daily for 7 days and 2000 mg metronidazole single dose, or 400 mg metronidazole 2× daily for 7 days | NG | 51 | 65 (33) | 80 (41) | 11 |
| CT | 44 | 69 (30) | 89 (39) | |||
| Or if pregnant: one intramuscular injection of 125 mg ceftriaxone and erythromycin 500 mg 4× daily for 7 days and 400 mg metronidazole 2× daily for 7 days | TV | 113 | 65 (73) | 88 (98) | ||
| NG | 11 | 100 (11) | 12 | |||
| Or if cervical excitation tenderness: 500 mg single dose ciprofloxacin and 100 mg of doxycycline 2× daily for 14 days, and 400 mg metronidazole 2× daily for 14 days | CT | 10 | 80 (8) | |||
| TV | 44 | 89 (39) | ||||
CT, Chlamydia trachomatis; HD, Haemophilus ducreyi; HSV-2, herpes simplex virus type 2; LGV, Lympho-granuloma venereum; NG, Neisseria gonorrhoeae; TP, Treponema pallidum; TV, Trichomonas vaginalis. Guidelines adapted from.6